SJF 8240 |
Catalog No.GC50753 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2230821-68-6
Sample solution is provided at 25 µL, 10mM.
c-MET degrader. Comprises MET inhibitor foretinib (GSK 1363089; ) joined by a linker to a von Hippel-Lindau (VHL) recruiting ligand. Degrades c-MET within 6 hours in vitro. Inhibits agonist-driven AKT phosphorylation and GTL16 cell proliferation (IC50 = 66.7 nM). Also degrades exon-14-deleted c-MET in Hs746T cells.
Review for SJF 8240
Average Rating: 5
(Based on Reviews and 26 reference(s) in Google Scholar.)Review for SJF 8240
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *