2'(3')-O-(N'-Methylanthraniloyl)guanosine-5'-O-triphosphate (sodium salt) |
| Catalog No.GC90862 |
Derivados fluorescentes de GTP
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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2'-O-(N-Metlanthraniloyl)guanosine-5'-O-triphosphate (2'-MANT-GTP) and 3'-MANT-GTP are fluorescent GTP derivatives, which undergo spontaneous isomerization.1 2'(3')-MANT-GTP inhibits mammalian adenylyl cyclase (AC1), AC2, and AC5 (Kis = 90, 610, and 53 nM, respectively), B. pertussis AC toxin CyaA (Kis = 5.9 and 16 µM, in the presence of manganese and magnesium, respectively), and B. anthracis AC toxin edema factor (Kis = 2.49 and 4.7 µM in the presence of manganese and magnesium, respectively).1,2,3
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