2-Oxopropanoate-13C5 sodium |
| Catalog No.GC72574 |
2-Oxopropanoate-13C5 sodium es el 13C marcado 2-oxopropanode sodio.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 89196-78-1
Sample solution is provided at 25 µL, 10mM.
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Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. S Nemoto, et al. Role for mitochondrial oxidants as regulators of cellular metabolism. Mol Cell Biol. 2000 Oct;20(19):7311-8.
[3]. W Zhao, et al. Fructose induced deactivation of antioxidant enzymes: preventive effect of pyruvate. Free Radic Res. 2000 Jul33(1):23-30.
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