3-epi-25-Hydroxy Vitamin D3-d6 |
| Catalog No.GC70854 |
3-epi-25-Hydroxy Vitamin D3-d6 es el deuterio labeled3-epi-25-hidroxi vitamina D3.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2483831-27-0
Sample solution is provided at 25 µL, 10mM.
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Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References:
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.
[2]. Nygaard RH, et al'. Metabolism of 25-Hydroxy-Vitamin D in Human Macrophages Is Highly Dependent on Macrophage Polarization. Int J Mol Sci. 2022 Sep 19;23(18):10943.
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