4,4'-Dimethoxybenzil (p-Anisil) |
Catalog No.GC33328 |
4,4'-Dimethoxybenzil (p-Anisil) es un inhibidor de la carboxil esterasa intestinal humana (hiCE) con Ki de 70 nM.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1226-42-2
Sample solution is provided at 25 µL, 10mM.
4,4'-Dimethoxybenzil is a human intestinal carboxyl esterase (hiCE) inhibitor with Ki of 70 nM.
By reducing irinotecaninduced diarrhea, hiCE inhibitors (e.g., 4,4'-Dimethoxybenzil, Compound 8) can improve the anti-cancer efficacy of irinotecan. To find effective hiCE inhibitors, a new virtual screening protocol that combines pharmacophore models derived from the hiCE structure and its ligands has been proposed[1].
[1]. GuoDong Zhang, et al. Predicting hiCE inhibitors based upon pharmacophore models derived from the receptor and its ligands. Science China Chemistry
Average Rating: 5
(Based on Reviews and 23 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *