8-iso Prostaglandin A2 (Synonyms: A2 Isoprostane, 15-A2t-IsoP, 15-A2t-Isoprostane, 8-epi PGA2, 8-iso PGA2) |
Catalog No.GC18781 |
Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids.
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Cas No.: 474391-66-7
Sample solution is provided at 25 µL, 10mM.
Isoprostanes are prostaglandin (PG)-like compounds produced in vivo by free radical-catalyzed peroxidation of arachidonoyl-containing lipids. 8-iso PGA2 is one of several isoprostanes produced from peroxidation of arachidonic acid esterified in phospholipids. 8-iso PGA2 is the dehydration product of 8-iso PGE2, a potent renal vasoconstrictor. Evidence for the in vivo production of 8-iso PGA2 has been shown in rat liver under conditions of oxidative stress. There are no published studies of the pharmacological properties of 8-iso PGA2.
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