8-iso Prostaglandin E2 (Synonyms: 8iso PGE2, 8epi PGE2) |
| Catalog No.GC41425 |
La 8-iso prostaglandina E2 (iPE2-III) es un miembro de la clase de prostanoides isoprostano.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 27415-25-4
Sample solution is provided at 25 µL, 10mM.
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8-iso PGE2 is one of several isoprostanes produced from arachidonic acid during lipid peroxidation. It is a potent renal vasoconstrictor in the rat. 8-iso PGE2 inhibits U-46619 or I-BOP-induced platelet aggregation with IC50 values of 0.5 and 5 µM, respectively. When infused into the renal artery of the rat at a concentration of 4 µg/kg/min, 8-iso PGE2 decreases the GFR and renal plasma flow by 80% without affecting blood pressure.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
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