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AChE/BChE/MAO-B-IN-1

Catalog No.GC70960

AChE/BChE/MAO-B-IN-1 (compuesto 10) es un inhibidor reversible y no dependiente del tiempo de AChE, BChE y MAO-B con valores de IC50 de 7.31, 0.56 y 26.1 μM para hAChE, hBChE y hMAO-B, respectivamente.

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AChE/BChE/MAO-B-IN-1 Chemical Structure

Cas No.: 2416910-82-0

Tamaño Precio Disponibilidad Cantidad
1 mg
108,00 $
Disponible
5 mg
252,00 $
Disponible
10 mg
360,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
AChE/BChE/MAO-B-IN-1 (Compound 10) is a reversible and non-time-dependent AChE, BChE and MAO-B inhibitor with IC50 values of 7.31, 0.56 and 26.1 μM for hAChE, hBChE and hMAO-B, respectively. AChE/BChE/MAO-B-IN-1 can cross the BBB and shows neuroprotective effects without cytotoxicity.

AChE/BChE/MAO-B-IN-1 (Compound 10) prevents amyloid β1-42 (Aβ1-42)-induced neuronal cell death[1].

References:
[1]. Košak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282.

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