Acid Ceramidase-IN-1 |
Catalog No.GC63530 |
Acid Ceramidase-IN-1 es un inhibidor de ceramidasa Ácida (AC, ASAH-1) potente y biodisponible por vÍa oral (hAC IC50 = 0,166 μM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2415225-30-6
Sample solution is provided at 25 µL, 10mM.
Acid Ceramidase-IN-1 is a potent and oral bioavailable acid ceramidase (AC, ASAH-1) inhibitor (hAC IC50=0.166 μM). Acid Ceramidase-IN-1 has excellent brain penetration in mice[1].
[1]. Di Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63(7):3634-3664.
Average Rating: 5
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