Acyline TFA |
Catalog No.GC71463 |
Acyline TFA, un análogo del péptido GnRH, es un antagonista de GnRH que inhilos niveles de gonadotropina y testosterona (T).
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
Acyline (50 μg, s.c., twice daily, 5 days) TFA can result in disruption of vaginal oestrus and reduce uterine weights in female Kiss1−/−and Gpr54−/− mice, as well as a decrease in luteinizing hormone (LH) concentrations of female Kiss1−/− mice[1].
Acyline (50 μg, s.c., once) TFA can reduce follicle stimulating hormone (FSH) concentrations from pre-acyline 1.51 ng/mL to post-acyline 1.27 ng/mL in male Kiss1−/− mice and from pre-acyline 2.87 ng/mL to post-acyline 1.95 ng/mL in male Gpr54−/− mice[1].
References:
[1]. Y M Chan, et al. Kisspeptin/Gpr54-independent gonadotrophin-releasing hormone activity in Kiss1 and Gpr54 mutant mice. J Neuroendocrinol. 2009 Dec;21(12):1015-23.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *