AKR1C3-IN-4 |
| Catalog No.GC62671 |
AKR1C3-IN-4 es un inhibidor potente y selectivo de la aldo-ceto reductasa 1C3 (AKR1C3) con una IC50 de 0,56 μM. AKR1C3-IN-4 tiene potencial para la investigaciÓn del cÁncer de prÓstata resistente a la castraciÓn (CPRC).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1284180-11-5
Sample solution is provided at 25 µL, 10mM.
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AKR1C3-IN-4 is a potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitor with an IC50 of 0.56 μM. AKR1C3-IN-4 has the potential for castrate resistant prostate cancer (CRPC) research[1].
AKR1C3-IN-4 has an IC50 of 15.1 μM for AKR1C2[1].
[1]. Adegoke O Adeniji, et al. Development of potent and selective inhibitors of aldo-keto reductase 1C3 (type 5 17β-hydroxysteroid dehydrogenase) based on N-phenyl-aminobenzoates and their structure-activity relationships. J Med Chem. 2012 Mar 8;55(5):2311-23.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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