Akt1&PKA-IN-1 |
| Catalog No.GC71063 |
Akt1&PKA-IN-1 es un potente inhibidor dual de Akt/PKA con valores de IC50 de 0.03, 0.11 μM, y 9.8 μM para PKAa, Akt, y CDK2, respectivamente.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1334107-58-2
Sample solution is provided at 25 µL, 10mM.
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Akt1&PKA-IN-1 is a potent dual Akt/PKA inhibitor with IC50 values of 0.03 , 0.11 μM, and 9.8 μM for PKAa, Akt, and CDK2, respectively. Akt1&PKA-IN-1 is selective for cyclin-dependent kinase 2 (CDK2).
References:
[1]. Ashton KS, et al. Design and synthesis of novel amide AKT1 inhibitors with selectivity over CDK2. Bioorg Med Chem Lett. 2011 Sep 15;21(18):5191-6.
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Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Akt1&PKA-IN-1
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