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(Ala13)-Apelin-13 TFA

Catalog No.GC72173

(Ala13)-Apelin-13 TFA es un potente antagonista de los receptores APJ.

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(Ala13)-Apelin-13 TFA Chemical Structure

Tamaño Precio Disponibilidad Cantidad
1 mg
45,00 $
Disponible
5 mg
117,00 $
Disponible
10 mg
180,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
(Ala13)-Apelin-13 TFA is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 TFA inhibits gastric motility through vagal cholinergic pathway.

(Ala13)-Apelin-13 TFA (1-300 pmol/60 nl; microinjected into the DVC) decreases gastric tone and motility in a dose-dependent manner in rats[1].

References:
[1]. Bülbül M, et al. Apelin-13 inhibits gastric motility through vagal cholinergic pathway in rats. Am J Physiol Gastrointest Liver Physiol. 2018 Feb 1;314(2):G201-G210.
[2]. O'Harte FPM,et al. Acylated apelin-13 amide analogues exhibit enzyme resistance and prolonged insulin releasing, glucose lowering and anorexic properties. Biochem Pharmacol. 2017 Dec 15;146:165-173.

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