Altertoxin I (Synonyms: Dihydroalterperylenol) |
| Catalog No.GC42772 |
La altertoxina I (dihidroalterperilenol) es una micotoxina de tipo quinona producida por el hongo Alternaria alternata, que es mutagénica y citotÓxica y puede alterar débilmente la comunicaciÓn metabÓlica.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 56258-32-3
Sample solution is provided at 25 µL, 10mM.
Altertoxin I (Dihydroalterperylenol) is a quinone-type mycotoxin produced by Alternaria alternata fungi, which is mutagenic and cytotoxic, and can weakly disrupts metabolic communication[1].
References:
[1]. Jarolim K, et al. Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II. Arch Toxicol. 2017 Jan;91(1):203-216.
[2]. Boutin BK, et al. Effects of purified altertoxins I, II, and III in the metabolic communication V79 system. J Toxicol Environ Health. 1989;26(1):75-81.
[3]. Stack ME, et al. Mutagenicity of the Alternaria metabolites altertoxins I, II, and III. Appl Environ Microbiol. 1986 Oct;52(4):718-22.
| Cas No. | 56258-32-3 | SDF | |
| Sinónimos | Dihydroalterperylenol | ||
| Chemical Name | (1S,12aR,12bS)-1,2,11,12,12a,12b-hexahydro-1,4,9,12a-tetrahydroxy-3,10-perylenedione | ||
| Canonical SMILES | O=C(CC[C@@]1(O)[C@@]([C@@H](O)C2)([H])C3=C4C=CC(O)=C3C2=O)C5=C1C4=CC=C5O | ||
| Formula | C20H16O6 | M.Wt | 352.3 |
| Solubility | 10mg/mL in dichloromethane | Storage | Store at -20°C |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 2.8385 mL | 14.1924 mL | 28.3849 mL |
| 5 mM | 0.5677 mL | 2.8385 mL | 5.677 mL |
| 10 mM | 0.2838 mL | 1.4192 mL | 2.8385 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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μL
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Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: ≥95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 25 reference(s) in Google Scholar.)
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