Antimalarial agent 33 |
| Catalog No.GC71332 |
Antimalarial agent 33 (compuesto 5g) tiene actividad antiplasmodial contra las etapas eritrocítica y hepática de Plasmodium con una EC50 de 1,1 μM para cepa K1 P. falciparum.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Antimalarial agent 33 (compound 5g) has antiplasmodial activity against erythrocytic and hepatic stages of Plasmodium with an EC50 of 1.1 μM for K1 P. falciparum strain. Antimalarial agent 33 demonstrats enhanced microsomal stability (T1/2=29 min). Antimalarial agent 33 has no significant cytotoxicity against primary hepatocytes.
References:
[1]. Prisca Lagardère, et al. Novel thienopyrimidones targeting hepatic and erythrocytic stages of Plasmodium parasites with increased microsomal stability. Eur J Med Chem. 2023 Dec 5:261:115873.
Review for Antimalarial agent 33
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Antimalarial agent 33
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