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APPA

Catalog No.GB40100

APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.

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APPA Chemical Structure

Cas No.: 100750-39-8

Tamaño Precio Disponibilidad Cantidad
10mg
347,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

APPA is an aldose reductase inhibitor with an IC50 value of 0.0223 μM. APPA could inhibit apoptosis in rat glomerular mesangial cells in vitro. In addition, APPA improved the pathological symptoms of streptozotocin-induced diabetic nephropathy (DN) in rats by affecting antioxidant activities and reducing the levels of TGF-β, collagen IV, and laminin.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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