AY254 |
Catalog No.GC72180 |
AY254 es un análogo de AY77.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2093408-03-6
Sample solution is provided at 25 µL, 10mM.
AY254 is an analogue of AY77 . AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling
References:
[1]. Jiang Y, et al. Biased Signaling by Agonists of Protease Activated Receptor 2. ACS Chem Biol. 2017 May 19;12(5):1217-1226.
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