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AY254

Catalog No.GC72180

AY254 es un análogo de AY77.

Products are for research use only. Not for human use. We do not sell to patients.

AY254 Chemical Structure

Cas No.: 2093408-03-6

Tamaño Precio Disponibilidad Cantidad
1 mg
665,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
AY254 is an analogue of AY77 . AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling

References:
[1]. Jiang Y, et al. Biased Signaling by Agonists of Protease Activated Receptor 2. ACS Chem Biol. 2017 May 19;12(5):1217-1226.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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