Bayer 18 |
Catalog No.GC91506 |
Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1251752-12-1
Sample solution is provided at 25 µL, 10mM.
Bayer 18 is a tyrosine kinase 2 (TYK2) inhibitor (IC50 = 18.7 nM).[1] It is selective for TYK2 over JAK2, cyclin-dependent kinase 2 (Cdk2), and VEGFR2 (IC50s = 2,000, 1,790, and 3,520 nM, respectively).
References:
[1].Buchmann, B., Eis, K., Bothe, U., et al.Aminocabonylamino-substituted anilino-pyrimidine derivatives as Tyk inhibitors, their production and use as medicinal products(2010).
Average Rating: 5
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