Bepotastine-d6 (besylate) (Synonyms: Bepotastine besilate-d6) |
| Catalog No.GC91436 |
Bepotastina-d6 está destinada para su uso como estándar interno en la cuantificación de bepotastina por GC- o LC-MS.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2469626-71-7
Sample solution is provided at 25 µL, 10mM.
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Bepotastine-d6 is intended for use as an internal standard for the quantification of bepotastine by GC- or LC-MS. Bepotastine is an antagonist of the histamine H1 receptor that is selective over H3, α1-, α2-, and β-adrenergic, dopamine D2long, serotonin 5-HT2, muscarinic acetylcholine, and benzodiazepine receptors.1 It reduces dye leakage from the nasal passages of rats acutely sensitized to an antigen (ED50 = 0.03 mg/kg) and inhibits histamine-induced bronchoconstriction in the anesthetized dog (ED50 = 3.2 µg/kg).2,3 Bepotastine prevents conjunctival vascular hyperpermeability in a guinea pig model of conjunctivitis in a dose-dependent manner.4 Formulations containing bepotastine have been used in the treatment of itching associated with allergic conjunctivitis.
Review for Bepotastine-d6 (besylate)
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Bepotastine-d6 (besylate)
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