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Bevonescein

Catalog No.GC72224

Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue.

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Bevonescein Chemical Structure

Cas No.: 2276787-79-0

Tamaño Precio Disponibilidad Cantidad
1 mg
99,00 $
Disponible
5 mg
290,00 $
Disponible
10 mg
387,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Bevonescein (ALM-488) is a novel, intravenously-administrated fluorescein-conjugated peptide that binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves.

Bevonescein (ALM-488; 900 nmol; IV; underwent a 90-minute observation period) improves nerve identification for intact, degenerated, and partially regenerated nerves by vivo realtime fluorescence imaging (FL) in female SKH‐1 hairless, wild‐type, ~25 g mice[1].

References:
[1]. Kayva L Crawford, et al. Identification of Degenerated Murine Facial Nerves With Fluorescence Labeling After Transection Injury. Otolaryngol Head Neck Surg. 2023 Aug;169(2):234-242.
[2]. Feredun Azari, et al. Intraoperative molecular imaging clinical trials: a review of 2020 conference proceedings. J Biomed Opt. 2021 May;26(5):050901. Feredun Azari, et al. Intraoperative molecular imaging clinical trials: a review of 2020 conference proceedings. J Biomed Opt. 2021 May;26(5):050901.

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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