Biotinylated isoxazole |
Catalog No.GB40123 |
Biotin-isoxazole (1377605-22-5) precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.
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Cas No.: 1377605-22-5
Sample solution is provided at 25 µL, 10mM.
Biotin-isoxazole (1377605-22-5) precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules. In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones. SR domains were found to be the determinant that facilitates B-Isox precipitation. Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.
Average Rating: 5
(Based on Reviews and 30 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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