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Biotinylated isoxazole

Catalog No.GB40123

Biotin-isoxazole (1377605-22-5) precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules.

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Biotinylated isoxazole Chemical Structure

Cas No.: 1377605-22-5

Tamaño Precio Disponibilidad Cantidad
1mg
300,00 $
Disponible
5mg
1.080,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Biotin-isoxazole (1377605-22-5) precipitates hundreds of RNA-binding proteins with significant overlap to the constituents of RNA granules. In one study roughly 580 nuclear proteins were identified as being precipitated by B-Isox including TAF15, RNA polymerase II (largest subunit), numerous subunits of the mediator complex as well as a variety of enzymes involved in epigenetic modification of histones. SR domains were found to be the determinant that facilitates B-Isox precipitation. Also allows for the fractionation / isolation of SG-associated proteins and RNA precipitates.

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