A ubiquitous metabolite that participates in numerous physiological processes, including transsulfuration, polyamine biosynthesis, and transmethylation is the ademetionine also known as S-adenosyl-L-methionine (AdoMet), SAM or SAMe ( Glpbio ).

A macrolide antibiotic, tylosin is active against gram-positive aerobic bacteria and mycoplasmas throughout a wide range of conditions. It is authorized for the treatment of a number of infectious disorders in cattle and poultry, including mastitis, respiratory conditions, and farm animal dysentery.

En números anteriores, presentamos diversas formulaciones y estrategias para la disolución de fármacos. Entre ellas, el DMSO, que no se recomienda, también tiene un lugar como co-disolvente, pero es bastante controvertido. El uso de este disolvente, restringido por la FDA, está ampliamente extendido y es altamente tóxico. ¿Qué tan tóxico es y cómo lo utilizamos en nuestros experimentos? Hoy revelaremos el uso correcto del "disolvente universal" DMSO en experimentos con células y animales.

Brent R. Stockwell, el autor que originó el concepto de ferroptosis, ha escrito una reseña sobre el progreso dela investigación en el 10.º aniversario dela ferroptosis, publicada en la revista Cell, conun alto factor de impacto de 66.85.

Introduction: RSM-932A, also known as TCD- 717, is a ChoKα asset, which targets the mortal choline kinase nascence, an enzyme involved in increased lipid metabolism of cancer cells. RSM-932A appears to have an altogether new medium of inhibition and is synergistic with respect to both choline and ATP. RSM-932A have in vitro inhibitory exertion in the low nanomolar range.