BMS905 |
Catalog No.GC71229 |
BMS905 es un inhibidual de TLR7 y TLR8 (IC50s: 0.7 y 3.2 nM respectivamente).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2205846-49-5
Sample solution is provided at 25 µL, 10mM.
BMS905 is an orally active TLR7 and TLR8 dual inhibitor (IC50s: 0.7 and 3.2 nM respectively). BMS905 inhibits TLR7 or TLR8 induced IL-6 production in human/mouse whole blood. BMS905 can be used for research of lupus.
References:
[1]. Sreekantha RK, et al. Identification of 2-Pyridinylindole-Based Dual Antagonists of Toll-like Receptors 7 and 8 (TLR7/8). ACS Med Chem Lett. 2022 Apr 25;13(5):812-818.
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Average Rating: 5
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