Boc-aminooxy-PEG5-propargyl |
| Catalog No.GC67125 |
Boc-aminooxy-PEG5-propargyl es un conector PROTAC basado en PEG que se puede utilizar en la síntesis de PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2086688-98-2
Sample solution is provided at 25 µL, 10mM.
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Boc-aminooxy-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.
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