C10 Ceramide (d18:1/10:0) (Synonyms: N-decanoyl-D-erythro-Sphingosine) |
| Catalog No.GC43004 |
C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 111122-57-7
Sample solution is provided at 25 µL, 10mM.
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C10 ceramide is an endogenous, bioactive sphingolipid produced by ceramide synthase. [1] C10 ceramide inhibits growth of wild-type and MDR1 gene-transfected MDA435/LCC6 human breast cancer cells with IC50 values of 44.1 and 46 μM, respectively. It also inhibits the growth of J774 murine macrophages in a dose-dependent manner.
Reference:
[1]. Shabbits, J.A., and Mayer, L.D. Intracellular delivery of ceramide lipids via liposomes enhances apoptosis in vitro. Biochim Biophys. Acta. 1612(1), 98-106 (2003).
Average Rating: 5 (Based on Reviews and 37 reference(s) in Google Scholar.)
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