CID44216842 (Synonyms: Cdc42-IN-1) |
| Catalog No.GC39810 |
CID44216842 (Cdc42-IN-1) es un potente inhibidor de plomo de uniÓn de nucleÓtido de guanina selectivo de Cdc42. Las CE50 para el mutante Cdc42 WT y Cdc42Q61L son 1,0 y 1,2 μM en el ensayo de uniÓn a GTP, respectivamente. Las CE50 para el mutante Cdc42 WT y Cdc42Q61L son 0,3 y 0,5 μM en el ensayo de uniÓn de GDP, respectivamente. Uso como sonda molecular.
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Cas No.: 1222513-26-9
Sample solution is provided at 25 µL, 10mM.
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CID44216842 (Cdc42-IN-1) is a potent Cdc42-selective guanine nucleotide binding lead inhibitor. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 1.0 and 1.2 μM in GTP binding assay, respectively. The EC50s for Cdc42 WT and Cdc42Q61L mutant are 0.3 and 0.5 μM in GDP binding assay, respectively. Use as a molecular probe[1].
[1]. Lin Hong, et al. Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe. J Biol Chem. 2013 Mar 22;288(12):8531-43.
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