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CX-157

Catalog No.GC31155

CX-157 es un inhibidor reversible de la monoaminooxidasa-A (MAO-A) con un EC50 de 19,3ng/mL.

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CX-157 Chemical Structure

Cas No.: 205187-53-7

Tamaño Precio Disponibilidad Cantidad
1mg
863,00 $
Disponible
5mg
1.381,00 $
Disponible
10mg
2.210,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL.

CX-157 is a reversible inhibitor of monoamine oxidase-A (MAO-A) with an EC50 of 19.3 ng/mL. CX-157 is an investigational compound currently in development for the treatment of major depressive disorder (MDD). Mechanistic studies in animals have shown that CX-157 acts to inhibit MAO-A activity in a reversible and competitive manner, elevating brain levels of monoamine neurotransmitters[1].

[1]. Fowler JS, et al. Reversible inhibitors of monoamine oxidase-A (RIMAs): robust, reversible inhibition of human brain MAO-A by CX157. Neuropsychopharmacology. 2010 Feb;35(3):623-31.

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