D-Lysine |
| Catalog No.GC67216 |
La D-lisina es una materia prima útil que se emplea como análogo de la hormona liberadora de hormona luteinizante y como vehículo de fármacos en forma de polilisina. La D-lisina disminuye la captación renal de radiactividad durante la gammagrafía y PRRT con baja toxicidad. D-Lisina no interfiere con el equilibrio metabólico natural de aminoácidos.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 923-27-3
Sample solution is provided at 25 µL, 10mM.
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D-Lysine is a useful raw material employed as an analog of lutenizing-hormone-releasing hormone and as a drug carrier in the form of polylysine. D-Lysine decreases renal uptake of radioactivity during scintigraphy and PRRT with low toxicity. D-Lysine not interferes with the natural amino acid metabolic balance[1][2].
D-Lysine (400 mg/kg; i.v. or p.o.) dose not result in significantly greater inhibition of kidney uptake of '"In-DTPAOC, and Oral administration of D-lysine also reduces kidney uptake in rats[1].
[1]. Bernard BF, et al. D-lysine reduction of indium-111 octreotide and yttrium-90 octreotide renal uptake. J Nucl Med. 1997 Dec;38(12):1929-33.
[2]. Takahashi E, et al. D-lysine production from L-lysine by successive chemical racemization and microbial asymmetric degradation. Appl Microbiol Biotechnol. 1997 Apr;47(4):347-51.
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