DC1-SMe |
| Catalog No.GC34190 |
DC1Sme, un derivado de DC1, exhibe valores IC50 de 22 pM, 10 pM, 32 pM y 250 pM para células cancerosas Ramos, Namalwa, HL60/s y COLO 205, respectivamente. DC1, un análogo del alquilador de ADN de unión al surco menor CC-1065, es una citotoxina ADC. DC1 se puede utilizar en la síntesis de conjugados de anticuerpo y fármaco para el tratamiento dirigido del cáncer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 501666-85-9
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
DC1-Sme is an antibody conjugate of phosphate prodrug of cytotoxic DNA alkylators for the targeted treatment of cancer.
[1]. Zhao RY, et al. Synthesis and biological evaluation of antibody conjugates of phosphate prodrugs of cytotoxic DNA alkylators for the targeted treatment of cancer. J Med Chem. 2012 Jan 26;55(2):766-82.
Average Rating: 5 (Based on Reviews and 32 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *