Didesethyl chloroquine |
Catalog No.GC60770 |
La cloroquina didesetilada (bisdesetilcloroquina) es un metabolito importante del fÁrmaco antipalÚdico cloroquina.
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Cas No.: 4298-14-0
Sample solution is provided at 25 µL, 10mM.
Didesethyl chloroquine (Bisdesethylchloroquine) is a major metabolite of the antimalarial drug Chloroquine. Didesethyl chloroquine is a potent myocardial depressant[1][2].
[1]. Biot C, et al. Synthesis and antimalarial activity in vitro of potential metabolites of ferrochloroquine and related compounds. Bioorg Med Chem. 1999 Dec;7(12):2843-7. [2]. Essien EE, et al. Effects of chloroquine and didesethylchloroquine on rabbit myocardium and mitochondria. J Pharm Pharmacol. 1986 Jul;38(7):543-6.
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