Diethylene glycol bis(p-toluenesulfonate) |
| Catalog No.GC60772 |
El bis(p-toluenosulfonato) de dietilenglicol es un conector PROTAC basado en PEG que se puede utilizar en la sÍntesis de PROTAC.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 7460-82-4
Sample solution is provided at 25 µL, 10mM.
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Diethylene glycol bis(p-toluenesulfonate) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
[1]. Snaebjornsson MT, et al. Non-canonical functions of enzymes facilitate cross-talk between cell metabolic and regulatory pathways. Exp Mol Med. 2018 Apr 16;50(4):34.
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