DL-Laudanosine |
Catalog No.GC61864 |
La DL-laudanosina, un metabolito de atracurio y cisatracurio, atraviesa la barrera hematoencefÁlica y puede provocar excitaciÓn y actividad convulsiva.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1699-51-0
Sample solution is provided at 25 µL, 10mM.
DL-Laudanosine, an Atracurium and Cisatracurium metabolite, crosses the blood-brain barrier and may cause excitement and seizure activity[1].
DL-Laudanosine (Laudanosine) appears to be unique in its ability to produce cerebral stimulation in lightly anaesthetized animals and it is reported to cause arousal from anaesthesia in subconvulsive doses[1].
References:
[1]. V Fodale, et al. Laudanosine, an Atracurium and Cisatracurium Metabolite. Eur J Anaesthesiol. 2002 Jul;19(7):466-73.
[2]. D J Chapple, et al. Cardiovascular and Neurological Effects of Laudanosine. Studies in Mice and Rats, and in Conscious and Anaesthetized Dogs. Br J Anaesth. 1987 Feb;59(2):218-25.
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