(E/Z)-E64FC26 |
| Catalog No.GC60402 |
(E/Z)-E64FC26 es un complejo de mezcla de E-E64FC26 y Z-E64FC26. E64FC26 (E-E64FC26) es un potente paninhibidor de la familia de la proteÍna disulfuro isomerasa (PDI), con IC50 de 1,9, 20,9, 25,9, 16,3 y 25,4 μM frente a PDIA1, PDIA3, PDIA4, TXNDC5 y PDIA6. E64FC26 muestra actividad antimieloma.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2285446-67-3
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity[1][2].
[1]. Nathan G. Dolloff, et al. Indene derivatives and uses thereof. US20190062298A1. [2]. Robinson RM, et al. Inhibitors of the protein disulfide isomerase family for the treatment of multiple myeloma. Leukemia. 2019 Apr;33(4):1011-1022.
Average Rating: 5 (Based on Reviews and 29 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *