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Enzaplatovir (Synonyms: BTA-C585)

Catalog No.GC62955

Enzaplatovir (BTA-C585) es un inhibidor de fusiÓn biodisponible por vÍa oral para la infecciÓn por el virus respiratorio sincitial (VSR).

Products are for research use only. Not for human use. We do not sell to patients.

Enzaplatovir Chemical Structure

Cas No.: 1323077-89-9

Tamaño Precio Disponibilidad Cantidad
5 mg
585,00 $
Disponible
10 mg
945,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of Enzaplatovir

Enzaplatovir (BTA-C585) is an orally bioavailable fusion inhibitor for respiratory syncytial virus (RSV) infection[1].

Respiratory syncytial virus (RSV)-associated lower respiratory tract infection (LRTI) imposes a substantial medical burden. Enzaplatovir is a small-molecule RSV entry inhibitor[1].

[1]. Eric A F SimÕes, et al. Past, Present and Future Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children. Infect Dis Ther. 2018 Mar;7(1):87-120.

Chemical Properties of Enzaplatovir

Cas No. 1323077-89-9 SDF
Sinónimos BTA-C585
Formula C20H19N5O3 M.Wt 377.4
Solubility DMSO : 200 mg/mL (529.94 mM; Need ultrasonic) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Enzaplatovir

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.6497 mL 13.2485 mL 26.4971 mL
5 mM 0.5299 mL 2.6497 mL 5.2994 mL
10 mM 0.265 mL 1.3249 mL 2.6497 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Enzaplatovir

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Enzaplatovir

Average Rating: 5 ★★★★★ (Based on Reviews and 15 reference(s) in Google Scholar.)

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