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Equilenin (Synonyms: (+)-Equilenin, d-Equilenin, NSC 9901)

Catalog No.GC18333

Equilenin is an equine estrogen found in the urine of pregnant mares.

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Equilenin Chemical Structure

Cas No.: 517-09-9

Tamaño Precio Disponibilidad Cantidad
500μg
170,00 $
Disponible
1mg
258,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of Equilenin

Equilenin is an equine estrogen found in the urine of pregnant mares. Unlike naturally occurring human estrogens, equilenin has no effect on nitric oxide synthase (eNOS) activity or expression and does not increase production of nitric oxide (NO). It is metabolized to 4-hydroxyequilenin, a carcinogenic compound that induces transformation of C3H 10T1/2 murine fibroblasts. Formulations containing equilenin conjugates have been widely used as hormone replacement therapies for post-menopausal women.

Chemical Properties of Equilenin

Cas No. 517-09-9 SDF
Sinónimos (+)-Equilenin, d-Equilenin, NSC 9901
Chemical Name 3-hydroxy-estra-1,3,5,7,9-pentaen-17-one
Canonical SMILES O=C1CC[C@@]([C@]1(C)CC2)([H])C3=C2C4=CC=C(O)C=C4C=C3
Formula C18H18O2 M.Wt 266.3
Solubility Acetonitrile: Soluble,DMSO: Soluble,Methanol: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Equilenin

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1 mg 5 mg 10 mg
1 mM 3.7552 mL 18.7758 mL 37.5516 mL
5 mM 0.751 mL 3.7552 mL 7.5103 mL
10 mM 0.3755 mL 1.8776 mL 3.7552 mL
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In vivo Formulation Calculator (Clear solution) of Equilenin

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for Equilenin

Average Rating: 5 ★★★★★ (Based on Reviews and 13 reference(s) in Google Scholar.)

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