Firazorexton hydrate |
| Catalog No.GC70783 |
Firazorexton hydrate (TAK-994) es un potente agonista del receptor de orexina tipo 2 (OX2R) (EC50: 19 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2861934-86-1
Sample solution is provided at 25 µL, 10mM.
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Firazorexton hydrate (TAK-994) is a potent, brain-penetrant, and orally active orexin type 2 receptor (OX2R) agonist (EC50: 19 nM). Firazorexton hydrate inhibits fragmentation of wakefulness and cataplexy-like episodes in mouse models of narcolepsy.
References:
[1]. Ishikawa T, et al. TAK-994, a Novel Orally Available Brain-Penetrant Orexin 2 Receptor-Selective Agonist, Suppresses Fragmentation of Wakefulness and Cataplexy-Like Episodes in Mouse Models of Narcolepsy. J Pharmacol Exp Ther. 2023 Jun;385(3):193-204.
Review for Firazorexton hydrate
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Firazorexton hydrate
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