Fmoc-NH-PEG8-CH2CH2COOH |
Catalog No.GC66177 |
Fmoc-NH-PEG8-CH2CH2COOH es un enlazador de ADC escindible que se utiliza en la sÍntesis de conjugados de anticuerpo-fÁrmaco (ADC).
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Cas No.: 756526-02-0
Sample solution is provided at 25 µL, 10mM.
Fmoc-NH-PEG8-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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