FTase Inhibitor I (Synonyms: Farnesyltransferase Inhibitor I) |
| Catalog No.GC18260 |
El inhibidor de FTasa I es un potente inhibidor de la farnesiltransferasa (FTasa; IC50 = 21 nM) que es más de 30 veces selectivo para la FTasa sobre la geranilgeranil transferasa (GGTase; IC50 = 790 nM).
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 149759-96-6
Sample solution is provided at 25 µL, 10mM.
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FTase inhibitor I is a potent inhibitor of farnesyltransferase (FTase; IC50 = 21 nM) that is greater than 30-fold selective for FTase over geranylgeranyl transferase (GGTase; IC50 = 790 nM). It prevents farnesylation of Ras and inhibits proliferation of cells transformed by Ras farnesylation. In a dog model of subarachnoid hemorrhage, it reduces GTP-Ras in spastic basilar arteries, decreases angiographic vasospasm, and improves clinical scores.
Review for FTase Inhibitor I
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
Review for FTase Inhibitor I
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
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