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Fuzapladib

Catalog No.GC71535

Fuzapladib (IS-741), un antígeno de activación tipo 1 (LFA-1), es una molécula de adhesión leucocitaria.

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Fuzapladib Chemical Structure

Cas No.: 141283-87-6

Tamaño Precio Disponibilidad Cantidad
1 mg
90,00 $
Disponible
5 mg
198,00 $
Disponible
10 mg
297,00 $
Disponible
25 mg
558,00 $
Disponible
50 mg
747,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Fuzapladib (IS-741), an orally active leukocyte-function-associated antigen type 1 (LFA-1) activation inhibitor, is a leukocyte adhesion molecule. Fuzapladib is also a phospholipase A2 (PLA2) inhibitor. Fuzapladib exerts anti-inflammatory effects by inhibiting leukocyte migration into the inflammatory site.

Fuzapladib (IS-741) (1 μM, 3 h) can significantly inhibit the adhesion of HL-60 cells to HUVEC under the stimulation of lipopolysaccharide[3].

Fuzapladib (IS-741) (p.o., 50 mg/kg, 7 days) inhibits neutrophil infiltration into inflamed lesions, and is effective for attenuating rat trinitrobenzene sulfonic acid (TNBS) ileitis[4].

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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