PEG6-(CH2CO2H)2 |
| Catalog No.GC36866 |
PEG6-(CH2CO2H)2 es un enlazador PEG PROTAC simétrico, para la sÍntesis de Homo-PROTAC, que son dimerizadores bivalentes de molécula pequeÑa de la ubiquitina ligasa VHL E3 para inducir la autodegradaciÓn.
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Cas No.: 77855-76-6
Sample solution is provided at 25 µL, 10mM.
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PEG6-(CH2CO2H)2 is a symmetric PEG PROTAC linker, for the synthesis of Homo-PROTACs which is bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation[1]. PEGs
[1]. Maniaci C, et al. Homo-PROTACs: bivalent small-molecule dimerizers of the VHL E3 ubiquitin ligase to induce self-degradation. Nat Commun. 2017 Oct 10;8(1):830.
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