SB 243213 hydrochloride |
| Catalog No.GC38173 |
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 200940-23-4
Sample solution is provided at 25 µL, 10mM.
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SB 243213 hydrochloride is a selective and high-affinity 5-hydroxytryptamine (5-HT)2C receptor antagonist with a pKi of 9.37 and a pKb of 9.8 for human 5-HT2C receptor. SB 243213 hydrochloride has improved anxiolytic profile[1].
SB-243213 hydrochloride is a potent inhibitor of central 5-HT2C receptor-mediated function in rats. SB-243213 hydrochloride exhibits anxiolytic-like activity in both the social interaction and Geller-Seifter conflict tests[1].
[1]. Wood MD, et al. SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety. Neuropharmacology. 2001 Aug;41(2):186-99.
Average Rating: 5 (Based on Reviews and 6 reference(s) in Google Scholar.)
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