TFMB-(R)-2-HG |
| Catalog No.GC38199 |
TFMB-(R)-2-HG, una versiÓn permeable a la membrana celular de (R)-2-HG, es un factor cancerÍgeno en la leucemia mieloide aguda (AML).TFMB-(R)-2-HG deteriora SCF ER- DiferenciaciÓn de células Hoxb8 en respuesta a la retirada de estrÓgenos.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1445700-01-5
Sample solution is provided at 25 µL, 10mM.
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TFMB-(R)-2-HG, a cell membrane-permeable version of (R)-2-HG, is a carcinogenic factor in Acute myeloid leukemia (AML).TFMB-(R)-2-HG impairs SCF ER-Hoxb8 cells differentiation in response to estrogen withdrawal[1].
[1]. Losman JA, et al. (R)-2-hydroxyglutarate is sufficient to promote leukemogenesis and its effects are reversible. Science. 2013 Mar 29;339(6127):1621-5.
Average Rating: 5 (Based on Reviews and 19 reference(s) in Google Scholar.)
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