Gefitinib impurity 1 |
| Catalog No.GC70645 |
Gefitinib impurity 1 es la impureza de Gefitinib.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 675126-26-8
Sample solution is provided at 25 µL, 10mM.
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Gefitinib impurity 1 is the impurity of Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity.
References:
[1]. Wakeling AE, et al. ZD1839: an orally active inhibitor of epidermal growth factor signaling with potential for cancer therapy. Cancer Res. 2002 Oct 15;62(20):5749-54.
Review for Gefitinib impurity 1
Average Rating: 5 (Based on Reviews and 30 reference(s) in Google Scholar.)
Review for Gefitinib impurity 1
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