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Glucocorticoid receptor agonist-2

Catalog No.GC71030

Glucocorticoid receptor agonist-2 (compuesto 21) es un agonista del receptor glucocorticoide con un valor de IC50 de 6,6 nM.

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Glucocorticoid receptor agonist-2 Chemical Structure

Cas No.: 2166378-92-1

Tamaño Precio Disponibilidad Cantidad
1 mg
306,00 $
Disponible
5 mg
765,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
Glucocorticoid receptor agonist-2 (compound 21) is an glucocorticoid receptor agonist with an IC50 value of 6.6 nM. Glucocorticoid receptor agonist-2 can be used to synthesize anti-inflammatory ADC molecules. Glucocorticoid receptor agonist-2 is an active reference of ABBV-3373.

Glucocorticoid receptor agonist-2 shows glucocorticoid receptor (GR) and progersterone receptor (PR) binding activities with IC50 values of 6.6 and 7.3 nM, respectively[1].
Glucocorticoid receptor agonist-2 shows EC50 values of 0.2 and 442 nM to glucocorticoid responsive element (GRE) reporter and mineralcorticoid receptor (MR), respectively[1].
Glucocorticoid receptor agonist-2 agonists MR with an EC50 value of 149 nM[1].

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