Glutaric acid |
Catalog No.GC33814 |
El Ácido glutÁrico, Ácido dicarboxÍlico C5, es un intermediario durante las vÍas catabÓlicas de la lisina y el triptÓfano.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 110-94-1
Sample solution is provided at 25 µL, 10mM.
Glutaric acid induces oxidative stress in brain of young rats.
Glutaric acid (GA) at concentrations of 1 and 2 mM is able to reduce TRAP measurement by up to 28% in a dose-dependent manner (β=0.77; P<0.001). Furthermore, a significantly inverse correlation is also verified between chemiluminescence and TRAP (β=0.81; P<0.001). Glutaric acid does not alter the activities of Cat and SOD, but strongly inhibits (up to 46%) the activity of GPx even at the lower concentration used (0.5 mM). It is observed that the metabolite inhibits this activity in a dose-dependent manner at concentrations as low as 0.05 mM[1].
[1]. de Oliveira Marques F, et al. acid induces oxidative stress in brain of young rats. Brain Res. 2003 Feb 21;964(1):153-8.
Average Rating: 5
(Based on Reviews and 26 reference(s) in Google Scholar.)GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *