GRP-60367 hydrochloride |
| Catalog No.GC60885 |
El clorhidrato de GRP-60367 es el primer inhibidor de entrada del virus de la rabia de molécula pequeÑa (RABV) con potencia nanomolar contra algunas cepas de RABV.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 2803211-60-9
Sample solution is provided at 25 µL, 10mM.
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GRP-60367 hydrochloride is a first-in-class small-molecule rabies virus (RABV) entry inhibitor with nanomolar potency against some RABV strains. GRP-60367 hydrochloride specifically targets the RABV G protein[1].
GRP-60367 (0.1 nM-1000 μM) confirms specific and potent anti-RABV activity of the scaffold, returning in dose-response assays EC50s ranging from 2 to 52 nM on different host cell lines[1]. Cell Viability Assay[1] Cell Line: BEAS-2B, 293T, or Hep-2 cell lines
[1]. Venice Du Pont, et al. Identification and Characterization of a Small-Molecule Rabies Virus Entry Inhibitor. J Virol. 2020 Jun 16;94(13):e00321-20.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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