Guvacine |
Catalog No.GC60890 |
La guvacina, un alcaloide que se encuentra en la nuez de Areca catechu, es un potente inhibidor de la captaciÓn de GABA.
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Cas No.: 498-96-4
Sample solution is provided at 25 µL, 10mM.
Guvacine, an alkaloid found in the nut of Areca catechu, is a potent GABA uptakp inhibitor. Guvacine inhibits rat GAT-1, rat GAT-2 and rat GAT-3 with IC50 values of 39 μM, 58 μM and 378 μM, respectively[1].
[1]. L A Borden, et al. Tiagabine, SK&F 89976-A, CI-966, and NNC-711 are selective for the cloned GABA transporter GAT-1. Eur J Pharmacol. 1994 Oct 14;269(2):219-24.
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