Hellebrigenin |
| Catalog No.GC64786 |
La hellebrigenina, una de las bufadienolidas pertenecientes a los esteroides cardioactivos, se aÍsla de la medicina tradicional china Venenum Bufonis. La hellebrigenina induce daÑo en el ADN y detenciÓn del ciclo celular G2/M. La hellebrigenina desencadena la apoptosis mediada por mitocondrias.
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Cas No.: 465-90-7
Sample solution is provided at 25 µL, 10mM.
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Hellebrigenin, one of bufadienolides belonging to cardioactive steroids, is isolated from traditional Chinese medicine Venenum Bufonis. Hellebrigenin induces DNA damage and cell cycle G2/M arrest. Hellebrigenin triggers mitochondria-mediated apoptosis.
[1]. Deng LJ, et al. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chem Biol Interact. 2014 Aug 5;219:184-94.
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