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iBRD4-BD1 diTFA

Catalog No.GC71159

iBRD4-BD1 diTFA es un inhibidor selectivo del bromodominio BRD4. iBRD4-BD1 diTFA tiene actividad de inhibición para el bromodominio BRD4 con un valor de IC50 de 12 nM.

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iBRD4-BD1 diTFA Chemical Structure

Cas No.: 2839318-20-4

Tamaño Precio Disponibilidad Cantidad
1 mg
297,00 $
Disponible
5 mg
743,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents
iBRD4-BD1 diTFA is selective BRD4 bromodomain inhibitor. iBRD4-BD1 diTFA has inhibition activity for BRD4 bromodomain with an IC50 value of 12 nM. iBRD4-BD1 diTFA can be used for the research of inflammation and oncology.

iBRD4-BD1 diTFA has affinity and selectivity for the BET-family BRD4-BD1 with an IC50 value of 12 nM[1].
iBRD4-BD1 diTFA has affinity and selectivity for the BET-family BRD4-BD2, BRD3-BD1, BRD3-BD2, BRD2-BD1 and BRD2-BD2 with IC50 values of 16 μM, 1.0 μM , 75 μM , 280 nM and 7.1 μM, respectively[1].
iBRD4-BD1 (0-50 μM; 72 h) diTFA has cytotoxicity with an EC50 value of 2.3 μM in MM.1S cells[1].

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