Ingenol ((-)-Ingenol) |
| Catalog No.GC32870 |
Ingenol ((-)-Ingenol) es un activador de PKC, con una Ki de 30 μM, con actividad antitumoral.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 30220-46-3
Sample solution is provided at 25 µL, 10mM.
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Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity.
Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1].
[1]. Hasler CM, et al. Specific binding to protein kinase C by ingenol and its induction of biological responses. Cancer Res. 1992 Jan 1;52(1):202-8.
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